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Temporal and Regional Regulation of Gene Expression by Calcium-Stimulated Adenylyl Cyclase Activity during Fear Memory

BACKGROUND: The Ca2+-stimulated adenylyl cyclases (ACs), AC1 and AC8, are key components of long-term memory processing. AC1 and AC8 double knockout mice (Adcy1(−/−)Adcy8(−/−); DKO) display impaired fear memory processing; the mechanism of this impairment is largely unknown. METHODOLOGY/PRINCIPAL FI...

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Detalles Bibliográficos
Autores principales:	Wieczorek, Lindsay, Maas, James W., Muglia, Lisa M., Vogt, Sherri K., Muglia, Louis J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954788/ https://www.ncbi.nlm.nih.gov/pubmed/20976279 http://dx.doi.org/10.1371/journal.pone.0013385

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