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Mono- or Double-Site Phosphorylation Distinctly Regulates the Proapoptotic Function of Bax
Bax is the major multidomain proapoptotic molecule that is required for apoptosis. It has been reported that phosphorylation of Bax at serine(S) 163 or S184 activates or inactivates its proapoptotic function, respectively. To uncover the mechanism(s) by which phosphorylation regulates the proapoptot...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954808/ https://www.ncbi.nlm.nih.gov/pubmed/20976235 http://dx.doi.org/10.1371/journal.pone.0013393 |