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Mono- or Double-Site Phosphorylation Distinctly Regulates the Proapoptotic Function of Bax

Bax is the major multidomain proapoptotic molecule that is required for apoptosis. It has been reported that phosphorylation of Bax at serine(S) 163 or S184 activates or inactivates its proapoptotic function, respectively. To uncover the mechanism(s) by which phosphorylation regulates the proapoptot...

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Detalles Bibliográficos
Autores principales:	Wang, Qinhong, Sun, Shi-Yong, Khuri, Fadlo, Curran, Walter J., Deng, Xingming
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954808/ https://www.ncbi.nlm.nih.gov/pubmed/20976235 http://dx.doi.org/10.1371/journal.pone.0013393

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