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A Covering Method for Detecting Genetic Associations between Rare Variants and Common Phenotypes
Genome wide association (GWA) studies, which test for association between common genetic markers and a disease phenotype, have shown varying degrees of success. While many factors could potentially confound GWA studies, we focus on the possibility that multiple, rare variants (RVs) may act in concer...
Autores principales: | Bhatia, Gaurav, Bansal, Vikas, Harismendy, Olivier, Schork, Nicholas J., Topol, Eric J., Frazer, Kelly, Bafna, Vineet |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954823/ https://www.ncbi.nlm.nih.gov/pubmed/20976246 http://dx.doi.org/10.1371/journal.pcbi.1000954 |
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