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Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction
Some polyunsaturated fatty acids (PUFAs), if not all, have been shown to have tumoricidal action, but their exact mechanism(s) of action is not clear. In the present study, we observed that n-6 PUFA linoleic acid (LA) inhibited tumor cell growth at high concentrations (above 300 μM); while low conce...
Autores principales: | Lu, Xiaofeng, Yu, Haining, Ma, Qi, Shen, Shengrong, Das, Undurti N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954911/ https://www.ncbi.nlm.nih.gov/pubmed/20868498 http://dx.doi.org/10.1186/1476-511X-9-106 |
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