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Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases. Quercetin, a plant flavonoid, is a potent antioxida...
Autores principales: | Ganesan, Shyamala, Faris, Andrea N, Comstock, Adam T, Chattoraj, Sangbrita S, Chattoraj, Asamanja, Burgess, John R, Curtis, Jeffrey L, Martinez, Fernando J, Zick, Suzanna, Hershenson, Marc B, Sajjan, Uma S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954923/ https://www.ncbi.nlm.nih.gov/pubmed/20920189 http://dx.doi.org/10.1186/1465-9921-11-131 |
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