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Differences in gut microbial metabolism are responsible for reduced hippurate synthesis in Crohn's disease

BACKGROUND: Certain urinary metabolites are the product of gut microbial or mammalian metabolism; others, such as hippurate, are mammalian-microbial 'co-metabolites'. It has previously been observed that Crohn's disease (CD) patients excrete significantly less hippurate than controls....

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Detalles Bibliográficos
Autores principales: Williams, Horace RT, Cox, I Jane, Walker, David G, Cobbold, Jeremy FL, Taylor-Robinson, Simon D, Marshall, Sara E, Orchard, Timothy R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954941/
https://www.ncbi.nlm.nih.gov/pubmed/20849615
http://dx.doi.org/10.1186/1471-230X-10-108