Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos

BACKGROUND: Unc-45 is a myosin chaperone and a Hsp90 co-chaperone that plays a key role in muscle development. Genetic and biochemical studies in C. elegans have demonstrated that Unc-45 facilitates the process of myosin folding and assembly in body wall muscles. Loss or overexpression of Unc-45 in...

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Detalles Bibliográficos
Autores principales: Bernick, Elena P, Zhang, Pei-Jun, Du, Shaojun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954953/
https://www.ncbi.nlm.nih.gov/pubmed/20849610
http://dx.doi.org/10.1186/1471-2121-11-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954953/
https://www.ncbi.nlm.nih.gov/pubmed/20849610
http://dx.doi.org/10.1186/1471-2121-11-70

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