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Dynamic instability of genomic methylation patterns in pluripotent stem cells
BACKGROUND: Genomic methylation patterns are established during gametogenesis, and perpetuated in somatic cells by faithful maintenance methylation. There have been previous indications that genomic methylation patterns may be less stable in embryonic stem (ES) cells than in differentiated somatic c...
Autores principales: | Ooi, Steen KT, Wolf, Daniel, Hartung, Odelya, Agarwal, Suneet, Daley, George Q, Goff, Stephen P, Bestor, Timothy H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954997/ https://www.ncbi.nlm.nih.gov/pubmed/20868487 http://dx.doi.org/10.1186/1756-8935-3-17 |
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