Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

Sequencing-based DNA methylation profiling methods are comprehensive and, as accuracy and affordability improve, will increasingly supplant microarrays for genome-scale analyses. Here, four sequencing-based methodologies were applied to biological replicates of human embryonic stem cells to compare...

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Detalles Bibliográficos
Autores principales: Harris, R. Alan, Wang, Ting, Coarfa, Cristian, Nagarajan, Raman P., Hong, Chibo, Downey, Sara L., Johnson, Brett E., Fouse, Shaun D., Delaney, Allen, Zhao, Yongjun, Olshen, Adam, Ballinger, Tracy, Zhou, Xin, Forsberg, Kevin J., Gu, Junchen, Echipare, Lorigail, O’Geen, Henriette, Lister, Ryan, Pelizzola, Mattia, Xi, Yuanxin, Epstein, Charles B., Bernstein, Bradley E., Hawkins, R. David, Ren, Bing, Chung, Wen-Yu, Gu, Hongcang, Bock, Christoph, Gnirke, Andreas, Zhang, Michael Q., Haussler, David, Ecker, Joseph, Li, Wei, Farnham, Peggy J., Waterland, Robert A., Meissner, Alexander, Marra, Marco A., Hirst, Martin, Milosavljevic, Aleksandar, Costello, Joseph F.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955169/
https://www.ncbi.nlm.nih.gov/pubmed/20852635
http://dx.doi.org/10.1038/nbt.1682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955169/
https://www.ncbi.nlm.nih.gov/pubmed/20852635
http://dx.doi.org/10.1038/nbt.1682

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