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Transcriptome Analysis Revealed Unique Genes as Targets for the Anti-inflammatory Action of Activated Protein C in Human Macrophages
BACKGROUND: Activated protein C (APC) has been introduced as a therapeutic agent for treatment of patients with severe sepsis due to its unique anticoagulant and anti-inflammatory properties in the vascular system. In this study we investigated novel targets for the anti-inflammatory action of APC i...
Autores principales: | Pereira, Claudia P., Bachli, Esther B., Schaer, Dominik J., Schoedon, Gabriele |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955553/ https://www.ncbi.nlm.nih.gov/pubmed/20976180 http://dx.doi.org/10.1371/journal.pone.0015352 |
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