FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemia

BACKGROUND: Mutations in FLT3 result in activated tyrosine kinase activity, cell growth stimulation, and a poor prognosis among various subtypes of leukemia. The causes and timing of the mutations are not currently known. We evaluated the prevalence and timing of origin of FLT3 mutations in a popula...

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Detalles Bibliográficos
Autores principales: Chang, Patrick, Kang, Michelle, Xiao, Anny, Chang, Jeffrey, Feusner, James, Buffler, Patricia, Wiemels, Joseph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955609/
https://www.ncbi.nlm.nih.gov/pubmed/20875128
http://dx.doi.org/10.1186/1471-2407-10-513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955609/
https://www.ncbi.nlm.nih.gov/pubmed/20875128
http://dx.doi.org/10.1186/1471-2407-10-513

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