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FLT3 mutation incidence and timing of origin in a population case series of pediatric leukemia
BACKGROUND: Mutations in FLT3 result in activated tyrosine kinase activity, cell growth stimulation, and a poor prognosis among various subtypes of leukemia. The causes and timing of the mutations are not currently known. We evaluated the prevalence and timing of origin of FLT3 mutations in a popula...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955609/ https://www.ncbi.nlm.nih.gov/pubmed/20875128 http://dx.doi.org/10.1186/1471-2407-10-513 |