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A structural-based statistical approach suggests a cooperative activity of PUM1 and miR-410 in human 3'-untranslated regions

BACKGROUND: Micro (mi)RNAs comprise a large family of small non-coding RNAs that are thought to regulate a large fraction of protein-coding genes. Generally, miRNAs downregulate messenger (m)RNA expression by binding to the 3' untranslated regions (UTRs) of the RNA molecules. An important facto...

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Detalles Bibliográficos
Autores principales: Leibovich, Limor, Mandel-Gutfreund, Yael, Yakhini, Zohar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955683/
https://www.ncbi.nlm.nih.gov/pubmed/20860814
http://dx.doi.org/10.1186/1758-907X-1-17