Cargando…
Large-Scale Analysis of Orthologs and Paralogs under Covarion-Like and Constant-but-Different Models of Amino Acid Evolution
Functional divergence between homologous proteins is expected to affect amino acid sequences in two main ways, which can be considered as proxies of biochemical divergence: a “covarion-like” pattern of correlated changes in evolutionary rates, and switches in conserved residues (“conserved but diffe...
Autores principales: | Studer, Romain A., Robinson-Rechavi, Marc |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955734/ https://www.ncbi.nlm.nih.gov/pubmed/20551039 http://dx.doi.org/10.1093/molbev/msq149 |
Ejemplares similares
-
Resolving the Ortholog Conjecture: Orthologs Tend to Be Weakly, but Significantly, More Similar in Function than Paralogs
por: Altenhoff, Adrian M., et al.
Publicado: (2012) -
PROCOV: maximum likelihood estimation of protein phylogeny under covarion models and site-specific covarion pattern analysis
por: Wang, Huai-Chun, et al.
Publicado: (2009) -
Tissue-Specificity of Gene Expression Diverges Slowly between Orthologs, and Rapidly between Paralogs
por: Kryuchkova-Mostacci, Nadezda, et al.
Publicado: (2016) -
The ortholog conjecture revisited: the value of orthologs and paralogs in function prediction
por: Stamboulian, Moses, et al.
Publicado: (2020) -
OPTIC: orthologous and paralogous transcripts in clades
por: Heger, Andreas, et al.
Publicado: (2008)