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Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca
Type I Baeyer–Villiger monooxygenases (BVMOs) strongly prefer NADPH over NADH as an electron donor. In order to elucidate the molecular basis for this coenzyme specificity, we have performed a site-directed mutagenesis study on phenylacetone monooxygenase (PAMO) from Thermobifida fusca. Using sequen...
Autores principales: | Dudek, Hanna M., Torres Pazmiño, Daniel E., Rodríguez, Cristina, de Gonzalo, Gonzalo, Gotor, Vicente, Fraaije, Marco W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956058/ https://www.ncbi.nlm.nih.gov/pubmed/20703875 http://dx.doi.org/10.1007/s00253-010-2769-y |
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