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Altered Expression of Signaling Genes in Jurkat Cells upon FTY720 Induced Apoptosis

FTY720, a novel immunosuppressant, has a marked activity in decreasing peripheral blood T lymphocytes upon oral administration. Recent investigations suggest that the action of FTY720 on lymphocytes may result from its ability to induce cell apoptosis. However, the cell signaling mechanism involved...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Tan, Wenfeng, Guo, Dunming, Zhu, Xiaomin, Qian, Keqing, He, Shaoheng
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956082/
https://www.ncbi.nlm.nih.gov/pubmed/20957081
http://dx.doi.org/10.3390/ijms11093087