Opioid inhibition of N-type Ca(2+) channels and spinal analgesia couple to alternative splicing

Alternative pre-mRNA splicing predominates in the nervous systems of complex organisms including humans dramatically expanding the potential size of the proteome. Cell-specific alternative pre-mRNA splicing is thought to optimize protein function for specialized cellular tasks, but direct evidence f...

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Detalles Bibliográficos
Autores principales: Andrade, Arturo, Denome, Sylvia, Jiang, Yu-Qiu, Marangoudakis, Spiro, Lipscombe, Diane
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956429/
https://www.ncbi.nlm.nih.gov/pubmed/20852623
http://dx.doi.org/10.1038/nn.2643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956429/
https://www.ncbi.nlm.nih.gov/pubmed/20852623
http://dx.doi.org/10.1038/nn.2643

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