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Opioid inhibition of N-type Ca(2+) channels and spinal analgesia couple to alternative splicing
Alternative pre-mRNA splicing predominates in the nervous systems of complex organisms including humans dramatically expanding the potential size of the proteome. Cell-specific alternative pre-mRNA splicing is thought to optimize protein function for specialized cellular tasks, but direct evidence f...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956429/ https://www.ncbi.nlm.nih.gov/pubmed/20852623 http://dx.doi.org/10.1038/nn.2643 |