A comprehensive methylome map of lineage commitment from hematopoietic progenitors

Epigenetic modifications must underlie lineage-specific differentiation as terminally differentiated cells express tissue-specific genes, but their DNA sequence is unchanged. Hematopoiesis provides a well-defined model to study epigenetic modifications during cell-fate decisions, as multipotent prog...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Hong, Ehrlich, Lauren I. R., Seita, Jun, Murakami, Peter, Doi, Akiko, Lindau, Paul, Lee, Hwajin, Aryee, Martin J., Irizarry, Rafael A., Kim, Kitai, Rossi, Derrick J, Inlay, Matthew A., Serwold, Thomas, Karsunky, Holger, Ho, Lena, Daley, George Q., Weissman, Irving L., Feinberg, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956609/
https://www.ncbi.nlm.nih.gov/pubmed/20720541
http://dx.doi.org/10.1038/nature09367

Ejemplares similares

Ejemplares similares