P130Cas Src-Binding and Substrate Domains Have Distinct Roles in Sustaining Focal Adhesion Disassembly and Promoting Cell Migration

The docking protein p130Cas is a prominent Src substrate found in focal adhesions (FAs) and is implicated in regulating critical aspects of cell motility including FA disassembly and protrusion of the leading edge plasma membrane. To better understand how p130Cas acts to promote these events we exam...

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Detalles Bibliográficos
Autores principales: Meenderink, Leslie M., Ryzhova, Larisa M., Donato, Dominique M., Gochberg, Daniel F., Kaverina, Irina, Hanks, Steven K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956669/
https://www.ncbi.nlm.nih.gov/pubmed/20976150
http://dx.doi.org/10.1371/journal.pone.0013412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956669/
https://www.ncbi.nlm.nih.gov/pubmed/20976150
http://dx.doi.org/10.1371/journal.pone.0013412

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