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Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones

Protease-activated receptors (PAR1-4) are activated by proteases released by cell damage or blood clotting, and are known to be involved in promoting pain and hyperalgesia. Previous studies have shown that PAR2 receptors enhance activation of TRPV1 but the role of other PARs is less clear. In this p...

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Detalles Bibliográficos
Autores principales:	Vellani, Vittorio, Kinsey, Anna M, Prandini, Massimiliano, Hechtfischer, Sabine C, Reeh, Peter, Magherini, Pier C, Giacomoni, Chiara, McNaughton, Peter A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956715/ https://www.ncbi.nlm.nih.gov/pubmed/20875131 http://dx.doi.org/10.1186/1744-8069-6-61

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