Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma

BACKGROUND: Hyaluronan accumulation correlates with the degree of malignancy in many solid tumor types, including malignant endometrial carcinomas. To elucidate the mechanism of hyaluronan accumulation, we examined the expression levels of the hyaluronan synthases (HAS1, HAS2 and HAS3) and hyaluroni...

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Detalles Bibliográficos
Autores principales: Nykopp, Timo K, Rilla, Kirsi, Tammi, Markku I, Tammi, Raija H, Sironen, Reijo, Hämäläinen, Kirsi, Kosma, Veli-Matti, Heinonen, Seppo, Anttila, Maarit
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956733/
https://www.ncbi.nlm.nih.gov/pubmed/20875124
http://dx.doi.org/10.1186/1471-2407-10-512

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