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The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA

DNA damage tolerance pathways facilitate the bypass of DNA lesions encountered during replication. These pathways can be mechanistically divided into recombinational damage avoidance and translesion synthesis, in which the lesion is directly bypassed by specialised DNA polymerases. We have recently...

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Detalles Bibliográficos
Autores principales: Phillips, Lara G., Sale, Julian E.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956782/
https://www.ncbi.nlm.nih.gov/pubmed/20691646
http://dx.doi.org/10.1016/j.dnarep.2010.07.006