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PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial

BACKGROUND: Innovative prevention strategies for HIV-1 transmission are urgently needed. PRO2000 vaginal gel was efficacious against HIV-1 transmission in studies in macaques; we aimed to assess efficacy and safety of 2% and 0·5% PRO2000 gels against vaginal HIV-1 transmission in women in sub-Sahara...

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Detalles Bibliográficos
Autores principales: McCormack, Sheena, Ramjee, Gita, Kamali, Anatoli, Rees, Helen, Crook, Angela M, Gafos, Mitzy, Jentsch, Ute, Pool, Robert, Chisembele, Maureen, Kapiga, Saidi, Mutemwa, Richard, Vallely, Andrew, Palanee, Thesla, Sookrajh, Yuki, Lacey, Charles J, Darbyshire, Janet, Grosskurth, Heiner, Profy, Albert, Nunn, Andrew, Hayes, Richard, Weber, Jonathan
Formato: Texto
Lenguaje:English
Publicado: Lancet Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956883/
https://www.ncbi.nlm.nih.gov/pubmed/20851460
http://dx.doi.org/10.1016/S0140-6736(10)61086-0