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Neurolysosomal pathology in human prosaposin deficiency suggests essential neurotrophic function of prosaposin
A neuropathologic study of three cases of prosaposin (pSap) deficiency (ages at death 27, 89 and 119 days), carried out in the standard autopsy tissues, revealed a neurolysosomal pathology different from that in the non-neuronal cells. Non-neuronal storage is represented by massive lysosomal accumul...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956888/ https://www.ncbi.nlm.nih.gov/pubmed/17024494 http://dx.doi.org/10.1007/s00401-006-0148-7 |