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The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population

Background. The aim of the present study was to examine sources of variation for serum cystatin C in a healthy Greek population. Methods. Cystatin C together with basic clinical chemistry tests was measured in a total of 490 adults (46 ± 16 yrs, 40% males) who underwent an annual health check. Demog...

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Autores principales: Evangelopoulos, Angelos A., Vallianou, Natalia G., Bountziouka, Vassiliki P., Giotopoulou, Amalia N., Bonou, Maria S., Barbetseas, John, Avgerinos, Peter C., Panagiotakos, Demosthenes B.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957100/
https://www.ncbi.nlm.nih.gov/pubmed/20976124
http://dx.doi.org/10.4061/2011/163281
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author Evangelopoulos, Angelos A.
Vallianou, Natalia G.
Bountziouka, Vassiliki P.
Giotopoulou, Amalia N.
Bonou, Maria S.
Barbetseas, John
Avgerinos, Peter C.
Panagiotakos, Demosthenes B.
author_facet Evangelopoulos, Angelos A.
Vallianou, Natalia G.
Bountziouka, Vassiliki P.
Giotopoulou, Amalia N.
Bonou, Maria S.
Barbetseas, John
Avgerinos, Peter C.
Panagiotakos, Demosthenes B.
author_sort Evangelopoulos, Angelos A.
collection PubMed
description Background. The aim of the present study was to examine sources of variation for serum cystatin C in a healthy Greek population. Methods. Cystatin C together with basic clinical chemistry tests was measured in a total of 490 adults (46 ± 16 yrs, 40% males) who underwent an annual health check. Demographic, anthropometric, and lifestyle characteristics were recorded. Results. Higher values of cystatin C were observed among males (P = .04), participants aged over 65 years (P < .001), current smokers (P = .001) and overweight/obese participants (P = .03). On the contrary, alcohol consumption and physical activity seemed to have no influence on cystatin C levels (P = .61; P = .95, resp.). Conclusions. In interpreting serum cystatin C values in a healthy adult population, age, gender, Body Mass Index, and cigarette smoking need to be considered, and determination of reference ranges among distinct subpopulations seem to be prudent.
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spelling pubmed-29571002010-10-25 The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population Evangelopoulos, Angelos A. Vallianou, Natalia G. Bountziouka, Vassiliki P. Giotopoulou, Amalia N. Bonou, Maria S. Barbetseas, John Avgerinos, Peter C. Panagiotakos, Demosthenes B. Cardiol Res Pract Research Article Background. The aim of the present study was to examine sources of variation for serum cystatin C in a healthy Greek population. Methods. Cystatin C together with basic clinical chemistry tests was measured in a total of 490 adults (46 ± 16 yrs, 40% males) who underwent an annual health check. Demographic, anthropometric, and lifestyle characteristics were recorded. Results. Higher values of cystatin C were observed among males (P = .04), participants aged over 65 years (P < .001), current smokers (P = .001) and overweight/obese participants (P = .03). On the contrary, alcohol consumption and physical activity seemed to have no influence on cystatin C levels (P = .61; P = .95, resp.). Conclusions. In interpreting serum cystatin C values in a healthy adult population, age, gender, Body Mass Index, and cigarette smoking need to be considered, and determination of reference ranges among distinct subpopulations seem to be prudent. SAGE-Hindawi Access to Research 2010-10-14 /pmc/articles/PMC2957100/ /pubmed/20976124 http://dx.doi.org/10.4061/2011/163281 Text en Copyright © 2011 Angelos A. Evangelopoulos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Evangelopoulos, Angelos A.
Vallianou, Natalia G.
Bountziouka, Vassiliki P.
Giotopoulou, Amalia N.
Bonou, Maria S.
Barbetseas, John
Avgerinos, Peter C.
Panagiotakos, Demosthenes B.
The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population
title The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population
title_full The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population
title_fullStr The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population
title_full_unstemmed The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population
title_short The Impact of Demographic Characteristics and Lifestyle in the Distribution of Cystatin C Values in a Healthy Greek Adult Population
title_sort impact of demographic characteristics and lifestyle in the distribution of cystatin c values in a healthy greek adult population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957100/
https://www.ncbi.nlm.nih.gov/pubmed/20976124
http://dx.doi.org/10.4061/2011/163281
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