Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor

Tenosynovial giant cell tumor is a neoplastic disease of joints that can cause severe morbidity. Recurrences are common following local therapy, and no effective medical therapy currently exists. Recent work has demonstrated that all cases overexpress macrophage colony-stimulating factor (CSF1), usu...

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Detalles Bibliográficos
Autores principales: Cheng, Hongwei, Clarkson, Paul W., Gao, Dongxia, Pacheco, Marina, Wang, Yuzhuo, Nielsen, Torsten O.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957133/
https://www.ncbi.nlm.nih.gov/pubmed/20981142
http://dx.doi.org/10.1155/2010/174528

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