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The Ndc80 kinetochore complex forms oligomeric arrays along microtubules
The Ndc80 complex is a key site of regulated kinetochore-microtubule attachment, but the molecular mechanism underlying its function remains unknown. Here we present a subnanometer resolution cryo-electron microscopy reconstruction of the human Ndc80 complex bound to microtubules, sufficient for pre...
Autores principales: | Alushin, Gregory M., Ramey, Vincent H., Pasqualato, Sebastiano, Ball, David A., Grigorieff, Nikolaus, Musacchio, Andrea, Nogales, Eva |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957311/ https://www.ncbi.nlm.nih.gov/pubmed/20944740 http://dx.doi.org/10.1038/nature09423 |
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