Cargando…
Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport
Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achi...
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957402/ https://www.ncbi.nlm.nih.gov/pubmed/20976043 http://dx.doi.org/10.1371/journal.pbio.1000516 |
_version_ | 1782188227782770688 |
---|---|
author | Heisler, Marcus G. Hamant, Olivier Krupinski, Pawel Uyttewaal, Magalie Ohno, Carolyn Jönsson, Henrik Traas, Jan Meyerowitz, Elliot M. |
author_facet | Heisler, Marcus G. Hamant, Olivier Krupinski, Pawel Uyttewaal, Magalie Ohno, Carolyn Jönsson, Henrik Traas, Jan Meyerowitz, Elliot M. |
author_sort | Heisler, Marcus G. |
collection | PubMed |
description | Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growth are linked through a correlated pattern of auxin efflux carrier localization and cortical microtubule orientation. Our experiments reveal that both PIN1 localization and microtubule array orientation are likely to respond to a shared upstream regulator that appears to be biomechanical in nature. Lastly, through mathematical modeling we show that such a biophysical coupling could mediate the feedback loop between auxin and its transport that underlies plant phyllotaxis. |
format | Text |
id | pubmed-2957402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-29574022010-10-25 Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport Heisler, Marcus G. Hamant, Olivier Krupinski, Pawel Uyttewaal, Magalie Ohno, Carolyn Jönsson, Henrik Traas, Jan Meyerowitz, Elliot M. PLoS Biol Research Article Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growth are linked through a correlated pattern of auxin efflux carrier localization and cortical microtubule orientation. Our experiments reveal that both PIN1 localization and microtubule array orientation are likely to respond to a shared upstream regulator that appears to be biomechanical in nature. Lastly, through mathematical modeling we show that such a biophysical coupling could mediate the feedback loop between auxin and its transport that underlies plant phyllotaxis. Public Library of Science 2010-10-19 /pmc/articles/PMC2957402/ /pubmed/20976043 http://dx.doi.org/10.1371/journal.pbio.1000516 Text en Heisler et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Heisler, Marcus G. Hamant, Olivier Krupinski, Pawel Uyttewaal, Magalie Ohno, Carolyn Jönsson, Henrik Traas, Jan Meyerowitz, Elliot M. Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport |
title | Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport |
title_full | Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport |
title_fullStr | Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport |
title_full_unstemmed | Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport |
title_short | Alignment between PIN1 Polarity and Microtubule Orientation in the Shoot Apical Meristem Reveals a Tight Coupling between Morphogenesis and Auxin Transport |
title_sort | alignment between pin1 polarity and microtubule orientation in the shoot apical meristem reveals a tight coupling between morphogenesis and auxin transport |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957402/ https://www.ncbi.nlm.nih.gov/pubmed/20976043 http://dx.doi.org/10.1371/journal.pbio.1000516 |
work_keys_str_mv | AT heislermarcusg alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT hamantolivier alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT krupinskipawel alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT uyttewaalmagalie alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT ohnocarolyn alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT jonssonhenrik alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT traasjan alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport AT meyerowitzelliotm alignmentbetweenpin1polarityandmicrotubuleorientationintheshootapicalmeristemrevealsatightcouplingbetweenmorphogenesisandauxintransport |