Control of HIF-1α and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock

Lung development requires coordinated signaling between airway and vascular growth, but the link between these processes remains unclear. Mammalian target of rapamycin complex-1 (mTORC1) can amplify hypoxia-inducible factor-1α (HIF-1α) vasculogenic activity through an NH(2)-terminal mTOR binding (TO...

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Detalles Bibliográficos
Autores principales: Scott, C. L., Walker, D. J., Cwiklinski, E., Tait, C., Tee, A. R., Land, S. C.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2010
Materias:
Editorial Focus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957420/
https://www.ncbi.nlm.nih.gov/pubmed/20622121
http://dx.doi.org/10.1152/ajplung.00348.2009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957420/
https://www.ncbi.nlm.nih.gov/pubmed/20622121
http://dx.doi.org/10.1152/ajplung.00348.2009

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