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The Structure and Mechanism of the Mycobacterium tuberculosis Cyclodityrosine Synthetase
The Mycobacterium tuberculosis enzyme Rv2275 catalyzes the formation of cyclo(L-Tyr-L-Tyr) using two molecules of Tyr-tRNA(Tyr) as substrates. The three-dimensional structure of Rv2275 was determined to 2.0 Å resolution, revealing that Rv2275 is structurally related to the class Ic aminoacyl-tRNA-sy...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957485/ https://www.ncbi.nlm.nih.gov/pubmed/20852636 http://dx.doi.org/10.1038/nchembio.440 |