Intestinal epithelia activate anti-viral signaling via intracellular sensing of rotavirus structural components

Rotavirus (RV), a leading cause of severe diarrhea, primarily infects intestinal epithelial cells (IEC) causing self-limiting illness. In order to better understand innate immunity to RV, we sought to define the extent to which IEC activation of anti-viral responses required viral replication or cou...

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Detalles Bibliográficos
Autores principales: Frias, Amena H., Vijay-Kumar, Matam, Gentsch, Jon R., Crawford, Sue E., Carvalho, Fred A., Estes, Mary K., Gewirtz, Andrew T.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957552/
https://www.ncbi.nlm.nih.gov/pubmed/20664578
http://dx.doi.org/10.1038/mi.2010.39

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