Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus

We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus–like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indic...

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Detalles Bibliográficos
Autores principales: Ilyushina, Natalia A., Kim, Jeong-Ki, Negovetich, Nicholas J., Choi, Young-Ki, Lang, Victoria, Bovin, Nicolai V., Forrest, Heather L., Song, Min-Suk, Pascua, Philippe Noriel Q., Kim, Chul-Joong, Webster, Robert G., Webby, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958019/
https://www.ncbi.nlm.nih.gov/pubmed/20113569
http://dx.doi.org/10.3201/eid1602.091141
Descripción
Sumario:We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus–like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indicating longstanding adaptation to mammals.

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