Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus

We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus–like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ilyushina, Natalia A., Kim, Jeong-Ki, Negovetich, Nicholas J., Choi, Young-Ki, Lang, Victoria, Bovin, Nicolai V., Forrest, Heather L., Song, Min-Suk, Pascua, Philippe Noriel Q., Kim, Chul-Joong, Webster, Robert G., Webby, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958019/
https://www.ncbi.nlm.nih.gov/pubmed/20113569
http://dx.doi.org/10.3201/eid1602.091141
_version_ 1782188291410362368
author Ilyushina, Natalia A.
Kim, Jeong-Ki
Negovetich, Nicholas J.
Choi, Young-Ki
Lang, Victoria
Bovin, Nicolai V.
Forrest, Heather L.
Song, Min-Suk
Pascua, Philippe Noriel Q.
Kim, Chul-Joong
Webster, Robert G.
Webby, Richard J.
author_facet Ilyushina, Natalia A.
Kim, Jeong-Ki
Negovetich, Nicholas J.
Choi, Young-Ki
Lang, Victoria
Bovin, Nicolai V.
Forrest, Heather L.
Song, Min-Suk
Pascua, Philippe Noriel Q.
Kim, Chul-Joong
Webster, Robert G.
Webby, Richard J.
author_sort Ilyushina, Natalia A.
collection PubMed
description We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus–like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indicating longstanding adaptation to mammals.
format Text
id pubmed-2958019
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-29580192010-11-01 Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus Ilyushina, Natalia A. Kim, Jeong-Ki Negovetich, Nicholas J. Choi, Young-Ki Lang, Victoria Bovin, Nicolai V. Forrest, Heather L. Song, Min-Suk Pascua, Philippe Noriel Q. Kim, Chul-Joong Webster, Robert G. Webby, Richard J. Emerg Infect Dis Dispatch We demonstrate that the novel pandemic influenza (H1N1) viruses have human virus–like receptor specificity and can no longer replicate in aquatic waterfowl, their historic natural reservoir. The biological properties of these viruses are consistent with those of their phylogenetic progenitors, indicating longstanding adaptation to mammals. Centers for Disease Control and Prevention 2010-02 /pmc/articles/PMC2958019/ /pubmed/20113569 http://dx.doi.org/10.3201/eid1602.091141 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Ilyushina, Natalia A.
Kim, Jeong-Ki
Negovetich, Nicholas J.
Choi, Young-Ki
Lang, Victoria
Bovin, Nicolai V.
Forrest, Heather L.
Song, Min-Suk
Pascua, Philippe Noriel Q.
Kim, Chul-Joong
Webster, Robert G.
Webby, Richard J.
Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
title Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
title_full Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
title_fullStr Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
title_full_unstemmed Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
title_short Extensive Mammalian Ancestry of Pandemic (H1N1) 2009 Virus
title_sort extensive mammalian ancestry of pandemic (h1n1) 2009 virus
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958019/
https://www.ncbi.nlm.nih.gov/pubmed/20113569
http://dx.doi.org/10.3201/eid1602.091141
work_keys_str_mv AT ilyushinanataliaa extensivemammalianancestryofpandemich1n12009virus
AT kimjeongki extensivemammalianancestryofpandemich1n12009virus
AT negovetichnicholasj extensivemammalianancestryofpandemich1n12009virus
AT choiyoungki extensivemammalianancestryofpandemich1n12009virus
AT langvictoria extensivemammalianancestryofpandemich1n12009virus
AT bovinnicolaiv extensivemammalianancestryofpandemich1n12009virus
AT forrestheatherl extensivemammalianancestryofpandemich1n12009virus
AT songminsuk extensivemammalianancestryofpandemich1n12009virus
AT pascuaphilippenorielq extensivemammalianancestryofpandemich1n12009virus
AT kimchuljoong extensivemammalianancestryofpandemich1n12009virus
AT websterrobertg extensivemammalianancestryofpandemich1n12009virus
AT webbyrichardj extensivemammalianancestryofpandemich1n12009virus

Ejemplares similares