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Combining QTL Data for HDL Cholesterol Levels from Two Different Species Leads to Smaller Confidence Intervals

QTL analysis detects regions of a genome that are linked to a complex trait. Once a QTL is detected, the region is narrowed via positional cloning in the hope of determining the underlying candidate gene – methods used include creating congenic strains, comparative genomics and gene expression analy...

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Detalles Bibliográficos
Autores principales: Cox, A, Sheehan, SM, Klöting, I, Paigen, B, Korstanje, R
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958246/
https://www.ncbi.nlm.nih.gov/pubmed/20551980
http://dx.doi.org/10.1038/hdy.2010.75