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Combining QTL Data for HDL Cholesterol Levels from Two Different Species Leads to Smaller Confidence Intervals
QTL analysis detects regions of a genome that are linked to a complex trait. Once a QTL is detected, the region is narrowed via positional cloning in the hope of determining the underlying candidate gene – methods used include creating congenic strains, comparative genomics and gene expression analy...
Autores principales: | Cox, A, Sheehan, SM, Klöting, I, Paigen, B, Korstanje, R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958246/ https://www.ncbi.nlm.nih.gov/pubmed/20551980 http://dx.doi.org/10.1038/hdy.2010.75 |
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