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Lafutidine, a Protective H(2) Receptor Antagonist, Enhances Mucosal Defense in Rat Esophagus

BACKGROUND: Luminal acid or CO(2) induces a hyperemic response in the esophagus, via activation of acid sensors on capsaicin-sensitive afferent nerves (CSAN). Since disruption of the hyperemic response to luminal CO(2) acidifies the interstitium of the esophageal mucosa, the hyperemic response may m...

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Detalles Bibliográficos
Autores principales: Akiba, Yasutada, Kaunitz, Jonathan D.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958262/
https://www.ncbi.nlm.nih.gov/pubmed/20824506
http://dx.doi.org/10.1007/s10620-010-1379-y