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Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat

The Drosophila genes fat (ft) and dachsous (ds) encode large atypical cadherins that collaborate to coordinately polarize cells in the plane of the epithelium (planar cell polarity) and to affect growth via the Warts/Hippo pathway [1–3]. Ft and Ds form heterodimeric bridges that convey polarity info...

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Detalles Bibliográficos
Autores principales: Brittle, Amy L., Repiso, Ada, Casal, José, Lawrence, Peter A., Strutt, David
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958304/
https://www.ncbi.nlm.nih.gov/pubmed/20434337
http://dx.doi.org/10.1016/j.cub.2010.03.056

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