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Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat
The Drosophila genes fat (ft) and dachsous (ds) encode large atypical cadherins that collaborate to coordinately polarize cells in the plane of the epithelium (planar cell polarity) and to affect growth via the Warts/Hippo pathway [1–3]. Ft and Ds form heterodimeric bridges that convey polarity info...
Autores principales: | Brittle, Amy L., Repiso, Ada, Casal, José, Lawrence, Peter A., Strutt, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958304/ https://www.ncbi.nlm.nih.gov/pubmed/20434337 http://dx.doi.org/10.1016/j.cub.2010.03.056 |
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