Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1

Talin binds to and activates integrins and is thought to couple them to cytoskeletal actin. However, functional studies on talin have been restricted by the fact that most cells express two talin isoforms. Here we show that human umbilical vein endothelial cells (HUVEC) express only talin1, and that...

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Detalles Bibliográficos
Autores principales: Kopp, Petra M., Bate, Neil, Hansen, Tania M., Brindle, Nicholas P.J., Praekelt, Uta, Debrand, Emmanuel, Coleman, Stacey, Mazzeo, Daniela, Goult, Benjamin T., Gingras, Alexandre R., Pritchard, Catrin A., Critchley, David R., Monkley, Susan J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958305/
https://www.ncbi.nlm.nih.gov/pubmed/20605055
http://dx.doi.org/10.1016/j.ejcb.2010.05.003

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