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Scoring function to predict solubility mutagenesis
BACKGROUND: Mutagenesis is commonly used to engineer proteins with desirable properties not present in the wild type (WT) protein, such as increased or decreased stability, reactivity, or solubility. Experimentalists often have to choose a small subset of mutations from a large number of candidates...
Autores principales: | Tian, Ye, Deutsch, Christopher, Krishnamoorthy, Bala |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958853/ https://www.ncbi.nlm.nih.gov/pubmed/20929563 http://dx.doi.org/10.1186/1748-7188-5-33 |
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