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Scoring function to predict solubility mutagenesis

BACKGROUND: Mutagenesis is commonly used to engineer proteins with desirable properties not present in the wild type (WT) protein, such as increased or decreased stability, reactivity, or solubility. Experimentalists often have to choose a small subset of mutations from a large number of candidates...

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Detalles Bibliográficos
Autores principales: Tian, Ye, Deutsch, Christopher, Krishnamoorthy, Bala
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958853/
https://www.ncbi.nlm.nih.gov/pubmed/20929563
http://dx.doi.org/10.1186/1748-7188-5-33

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