Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)

BACKGROUND: The liver X receptors (LXR) α and β regulate lipid and carbohydrate homeostasis and inflammation. Lxrβ(-/- )mice are glucose intolerant and at the same time lean. We aimed to assess the associations between single nucleotide polymorphisms (SNPs) in LXRβ and risk of type 2 diabetes mellit...

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Detalles Bibliográficos
Autores principales: Solaas, Karianne, Legry, Vanessa, Retterstol, Kjetil, Berg, Paul R, Holven, Kirsten B, Ferrières, Jean, Amouyel, Philippe, Lien, Sigbjorn, Romeo, Javier, Valtueña, Jara, Widhalm, Kurt, Ruiz, Jonatan R, Dallongeville, Jean, Tonstad, Serena, Rootwelt, Helge, Halvorsen, Bente, Nenseter, Marit S, Birkeland, Kare I, Thorsby, Per M, Meirhaeghe, Aline, Nebb, Hilde I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958901/
https://www.ncbi.nlm.nih.gov/pubmed/20939869
http://dx.doi.org/10.1186/1471-2350-11-144

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