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TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke
BACKGROUND: TGFβ is both neuroprotective and a key immune system modulator and is likely to be an important target for future stroke therapy. The precise function of increased TGF-β1 after stroke is unknown and its pleiotropic nature means that it may convey a neuroprotective signal, orchestrate gli...
Autores principales: | Doyle, Kristian P, Cekanaviciute, Egle, Mamer, Lauren E, Buckwalter, Marion S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958905/ https://www.ncbi.nlm.nih.gov/pubmed/20937129 http://dx.doi.org/10.1186/1742-2094-7-62 |
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