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Association between the Cytotoxic T-Lymphocyte Antigen 4 +49G > A polymorphism and cancer risk: a meta-analysis

BACKGROUND: As a key gene in the immunosurveillance of cell malignancy, Cytotoxic T-lymphocyte antigen 4 (CTLA-4 is an important negative regulator of T cell activation and proliferation. The CTLA-4 +49G > A polymorphism is one of the most commonly studied polymorphisms in this gene due to its as...

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Detalles Bibliográficos
Autores principales: Zheng, Jian, Yu, Xiao, Jiang, Lan, Xiao, Mang, Bai, Bing, Lu, Jiachun, Zhou, Yifeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958938/
https://www.ncbi.nlm.nih.gov/pubmed/20920330
http://dx.doi.org/10.1186/1471-2407-10-522