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Differential regulation of p53 function by the N-terminal ΔNp53 and Δ113p53 isoforms in zebrafish embryos

BACKGROUND: The p53 protein family coordinates stress responses of cells and organisms. Alternative promoter usage and/or splicing of p53 mRNA gives rise to at least nine mammalian p53 proteins with distinct N- and C-termini which are differentially expressed in normal and malignant cells. The human...

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Detalles Bibliográficos
Autores principales: Davidson, William R, Kari, Csaba, Ren, Qing, Daroczi, Borbala, Dicker, Adam P, Rodeck, Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958959/
https://www.ncbi.nlm.nih.gov/pubmed/20929554
http://dx.doi.org/10.1186/1471-213X-10-102

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