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Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis

BACKGROUND: There are no proven therapies that modify the structural changes associated with osteoarthritis (OA). Preclinical data suggests that intra-articular recombinant human BMP-7 (bone morphogenetic protein-7) has reparative effects on cartilage, as well as on symptoms of joint pain. The objec...

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Detalles Bibliográficos
Autores principales:	Hunter, David J, Pike, Marilyn C, Jonas, Beth L, Kissin, Eugene, Krop, Julie, McAlindon, Tim
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958989/ https://www.ncbi.nlm.nih.gov/pubmed/20932341 http://dx.doi.org/10.1186/1471-2474-11-232

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