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Structural and antimicrobial properties of human pre-elafin/trappin-2 and derived peptides against Pseudomonas aeruginosa

BACKGROUND: Pre-elafin/trappin-2 is a human innate defense molecule initially described as a potent inhibitor of neutrophil elastase. The full-length protein as well as the N-terminal "cementoin" and C-terminal "elafin" domains were also shown to possess broad antimicrobial activ...

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Detalles Bibliográficos
Autores principales: Bellemare, Audrey, Vernoux, Nathalie, Morin, Sébastien, Gagné, Stéphane M, Bourbonnais, Yves
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958999/
https://www.ncbi.nlm.nih.gov/pubmed/20932308
http://dx.doi.org/10.1186/1471-2180-10-253

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