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Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation
BACKGROUND: Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1β and IL-18, which are closely related to the induction of inflammation. However, limited evidence addresses the participation of caspase-1 in inflammatory pain. Here, we investigated the role of caspase...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959021/ https://www.ncbi.nlm.nih.gov/pubmed/20920345 http://dx.doi.org/10.1186/1744-8069-6-63 |