Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation

BACKGROUND: Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1β and IL-18, which are closely related to the induction of inflammation. However, limited evidence addresses the participation of caspase-1 in inflammatory pain. Here, we investigated the role of caspase...

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Detalles Bibliográficos
Autores principales: Cunha, Thiago M, Talbot, Jhimmy, Pinto, Larissa G, Vieira, Silvio M, Souza, Guilherme R, Guerrero, Ana T, Sonego, Fabiane, Verri, Waldiceu A, Zamboni, Dario S, Ferreira, Sergio H, Cunha, Fernando Q
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959021/
https://www.ncbi.nlm.nih.gov/pubmed/20920345
http://dx.doi.org/10.1186/1744-8069-6-63

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