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Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C

BACKGROUND: HIV-1 subtype C infections account for over half of global HIV infections, yet the vast focus of HIV-1 research has been on subtype B viruses which represent less than 12% of the global pandemic. Since HIV-1 reverse transcriptase (RT) is a major target of antiviral therapy, and since dif...

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Detalles Bibliográficos
Autores principales: Xu, Hong-Tao, Quan, Yudong, Asahchop, Eugene, Oliveira, Maureen, Moisi, Daniella, Wainberg, Mark A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959035/
https://www.ncbi.nlm.nih.gov/pubmed/20929562
http://dx.doi.org/10.1186/1742-4690-7-80